Angiotensin II Human

Angiotensin is a kind of peptide substance that has a strong vasoconstrictor and stimulates the secretion of aldosterone from the adrenal cortex. It is involved in the regulation of blood pressure and body fluids. It can be divided into angiotensin I-VII, and there are more studies in angiotensin I, angiotensin II, and angiotensin III.

Vasoconstrictors mainly play a role in relieving nasal congestion by stimulating α receptors on blood vessels to constrict blood vessels and reduce edema. This kind of drug is widely used in rhinitis patients, and can directly act on nasal drops on the nasal mucosa, such as zoline nasal drops, fura nasal drops, etc.

However, vasoconstrictors should be used with caution. If used blindly and irregularly, it may lead to the occurrence of drug-induced rhinitis. Therefore, these drugs are usually used for a limited period of time, generally not for more than a week, no more than 2-3 times a day. It is only recommended for those with nasal congestion so severe as to preclude the use of other nasal medications (e.g., nasal sprays with corticosteroids or antihistamines) and for those who have difficulty sleeping during the acute phase of rhinitis.

Vasoconstrictors mainly have the following effects:

Improve nasal congestion: Vasoconstrictors can stimulate vasoconstriction and reduce edema, thereby improving nasal congestion symptoms.

Prolonging the effect of anesthetic: During the operation, mixing vasoconstrictors with anesthetics can delay the absorption rate of anesthetics and prolong the effect of anesthesia.

Hemostasis: Vasoconstrictors can constrict blood vessels and reduce bleeding.

Increases blood pressure: In cases of low blood pressure, vasoconstrictors can raise blood pressure.

Relieves local pain: By constricting blood vessels, vasoconstrictors can reduce local pain.

Vasoconstrictors can be used in the following areas:

Surgery: During surgery, vasoconstrictors can be used to constrict blood vessels, reduce the amount of bleeding during surgery, and help control bleeding at the surgical site.

ENT: In otolaryngology, vasoconstrictors are often used to solve nasal congestion by constricting blood vessels to reduce mucosal congestion and improve nasal congestion.

Medical diseases: In medical diseases, vasoconstrictors can be used to improve the symptoms of arrhythmias, heart failure, and other diseases.

Precautions for the use of vasoconstrictors include:

Not for long-term use:

Vasoconstrictors can only be used as an adjunct to relieve nasal congestion symptoms, not for long-term use, and the general course of treatment should not exceed 7 days.

Newborns, infants and young children should not be used as much as possible: the nasal mucosa of this kind of people is weak, the blood vessels are abundant, and when the nasal mucosa is congested and edema, the vascular permeability increases, and the absorption is rapid after dropping, which is easy to be poisoned. When nasal congestion occurs, a hot towel can be applied to the nose and forehead, and a cotton swab is used to remove nasal discharge and foreign bodies.

Use with caution in patients with hypertension:

Vasoconstrictors constrict blood vessels cause blood pressure to rise, and even "hypertensive crisis".

Master the correct nasal dripping method:

Tilt your head back as much as possible, so that your chin is facing the sky, or lie on your side so that the side wall of the nasal cavity is horizontal and slightly oblique to the root of the nose, and drop the medicine.

The above information is for reference only, it is recommended to consult a professional doctor for more accurate information.

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