SLU-PP-332 Capsules

SLU-PP-332 is a synthetic estrogen-related receptor (ERR) agonist developed for experimental research into cellular energy metabolism and exercise-associated molecular signaling.

ERRs are a family of orphan nuclear receptors that play important roles in regulating genes involved in energy metabolism. ERRα, in particular, has a strong relationship with the PGC-1α signaling network and metabolic tissues with high energy demands.

SLU-PP-332 was reported as a synthetic pan-ERR agonist capable of activating ERRα, ERRβ and ERRγ, with the strongest activity toward ERRα. Reported EC50 values are approximately 98 nM for ERRα, 230 nM for ERRβ and 430 nM for ERRγ.

Important Classification

SLU-PP-332 is NOT a peptide.

It is a synthetic small molecule and nuclear receptor agonist.

slu-pp-332  Chemical Structure

OEM capsules

The research mechanism can be simplified as:

SLU-PP-332

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Activates ERRα / ERRβ / ERRγ

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Regulates ERR-dependent transcription

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Influences mitochondrial and oxidative metabolism pathways

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Changes expression of exercise-associated metabolic genes

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Supports investigation of cellular energy utilization and exercise-mimetic signaling

The relationship between ERRs and PGC-1α is well established in metabolic research. PGC-1α acts as an important transcriptional coactivator for ERRα and is involved in regulating genes associated with energy production and utilization.

In the original SLU-PP-332 research, treatment increased mitochondrial respiration in skeletal muscle cells and activated an ERRα-dependent acute aerobic exercise gene program.

Item	Specification	Test result		Test Method
Appearance	White to off-white powder	Complies		Visible
Identification	1HNMR Conforms to structure LCMS  Conforms to MW	Complies Complies		USP <197> USP <197>
Purity	≥99.0%	99.88%		HPLC
Water	≤0.5%	0.27%		USP <731>
Residue on ignition	≤0.2%	0.12%		USP <281>
Heavy metal	≤10pp	Complies		USP <233>
Ethanol	≤0.5%	0.019%		USP <611>

Storage	Store in a well-closed and dry place with room temperature and no direct sun light.
Conclusion	This product conforms to the specifications.
Shelf life	24months

SLU PP 332 HPLC report 

OEM

Capsule size	1mg,20mg,50mg,100mg and custom	Spec.:	30,60,90,120 pills/bottle
Custom formula	Support	Custom label	Support
Custom package	Support	Custom brand	Support

OEM Vegan Capsules

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All raw materials through independent laboratory testing, we control raw material quality from the source.

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3.Micron-Level Precision Quality Control:

A visual inspection system captures and analyzes product images to accurately screen for defects, cracks, scratches, color differences, and other issues, ensuring consistent and stable product quality.

4.Fully Automated Packaging:

Aseptic packaging throughout the entire process, equipped with sensor-operated sealing and automatic capping equipment, ensures precise sealing, eliminates human contamination, and meets high-end production standards.

5.Identity Testing

Confirms that the material corresponds to the intended compound.

6.HPLC Purity

HPLC analysis is commonly used to assess chemical purity.

 

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