What's orlistat powder?
Orlistat is a long-acting and potent specific gastrointestinal lipase inhibitor, white or off-white powder at room temperature, insoluble in water, soluble in chloroform, and easily soluble in ethanol, through the stomach and small intestine The active serine sites of gastric lipase and pancreatic lipase form a covalent bond to inactivate the enzymes. The fat in food cannot be decomposed into free fatty acids and monoacylglycerol, so the fat cannot be absorbed and utilized, thereby reducing the body's calorie intake and controlling body weight. At usual doses, fat absorption can be inhibited by 30%. It is rarely absorbed after oral administration and can be metabolized and inactivated in the intestinal tract. About 97% of this product is excreted with feces, of which 83% is in the original form.
Product name: Orlistat
CAS: 96829-58-2
MF: C29H53NO5
Molecular Weight: 495.73
Perform standard: USP, Enterprise standard
Appearance: White to off-white fine powder or fine powder with lumps
The Characters of Orlistat
1)Solubility: Orlistat is insoluble in water, but can be dissolved with fat.
2) Thermal stability: Orlistat can remain stable at high temperature without decomposition or deterioration.
3) Low viscosity: Orlistat has a low viscosity, which allows it to be evenly distributed in food.
4) Transparency: Orlistat is colorless and transparent, and will not change the appearance or color of food.
5) Not easily absorbed by the body: Orlistat will not be decomposed by enzymes in the human digestive system, so it cannot be absorbed and metabolized, thereby reducing the intake of calories.
Function
1)Relieve stomach pain and heartburn caused by hyperacidity: Orlistat can inhibit the activity of the proton pump on the stomach wall responsible for the secretion of gastric acid, reduce the secretion of gastric acid, thereby relieving the symptoms of stomach pain and heartburn.
2)Control acid reflux: Orlistat can reduce the secretion of gastric acid and reduce the occurrence of acid reflux, thereby reducing the discomfort caused by acid reflux.
3)Treatment of peptic ulcer: Orlistat can reduce the secretion of gastric acid, help the healing of peptic ulcer, and prevent the recurrence of ulcer.
4)Prevent gastric mucosal damage caused by non-steroidal anti-inflammatory drugs (NSAIDs): Orlistat can reduce gastric acid secretion caused by NSAIDs and reduce the risk of gastric mucosal damage.
5)The mechanism of action of orlistat is to suppress appetite by interacting with the appetite center in the brain. It can increase satiety, reduce food intake, and prolong the duration of satiety. In addition, orlistat can also reduce the craving for high-calorie food, making it easier for people to control their diet.
Orlistat can also increase the basal metabolic rate, and promote fat-burning and energy consumption.
6)Treatment of gastroesophageal reflux disease (GERD): Orlistat can reduce the secretion of gastric acid and improve the symptoms of gastroesophageal reflux disease, such as acid reflux and burning sensation in the chest.
Specification
|
Product Name |
Orlistat powder |
Batch Quantity |
500kg |
|
CAS |
96829-58-2 |
Analysis Date |
Aug. 29, 2021 |
|
Manufacture Date |
20210829 |
Package |
25kgs/drum |
|
Shelf time |
2 Years |
Purity |
99.6% |
|
Storage |
Preserve in tight containers, in a cool, dry place. |
||
|
Item |
Results |
Specifications |
|
|
Description |
White or almost white crystalline powder,smell-less |
Conforms |
|
|
Identification |
The result of HPLC is consistent with the reference one. The result of IR is consistent with the reference one. |
Conforms |
|
|
Melting Point |
42~46°C |
43~44°C |
|
|
Specific rotation |
-31.0°~ -37.0°(CHCl3,C=1) |
-34.5° |
|
|
Total impurity |
Not more than 2.0% |
0.71% |
|
|
Single impurity |
Not more than 0.30% |
0.21% |
|
|
Residual solvents |
Methanol≤3000ppm |
29.7ppm |
|
|
n-Heptane≤5000ppm |
63ppm |
||
|
Chloride |
Not more than 200ppm |
conforms |
|
|
Sulphate |
Not more than 500ppm |
conforms |
|
|
Residual on Ignition |
Not more than 1000ppm |
conforms |
|
|
Heavy metal |
Not more than 20ppm |
Conforms |
|
|
Essay |
98.5%---101.5% |
99.6% |
|
|
Result: The results conform with the USP-38 specification |
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1H NMR: Predict
Herben Good Review
Herben supplies many different products like Orlistat powder, L-carnitine, powder, hydrolyzed fish collagen, NMN, green tea extract, grape seed extract, and many different plant extract powders. We have many different clients from all over the world and have many good reviews from them.
Herben Factory
Herben Biotech has been a professional supplier of Orlistat for more than 10 years and has experience in importing to many different countries.
How to ship by Herben?
No matter you are new one or experienced importer, we will supply you the smooth service to help you get the order well.We can ship by DHL, FedEx, UPS, EMS, air ,train and sea.
FAQ
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For the high-value product, our MOQ starts from 10g,100g, and 1kg.
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A: First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
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